朱旆億 (Pei-Yi Chu)

Department of Post-Baccalaureate Medicine, College | Associate Professor and Associate Director

論文著作

Papers
1.Chen PM, Huang YH, Chen HH, Chu PY. Catalase Expression Is an Independent Prognostic Marker in Lung Adenocarcinoma. Anticancer Res. 2024 Jan;44(1):287-300. doi: 10.21873/anticanres.16811. PMID: 38159982.

2.Kuo WH, Chu PY¥, Wang CC, Huang PS, Chan SH. MAP7D3, a novel prognostic marker for triple-negative breast cancer, drives cell invasiveness and cancer-initiating cell properties to promote metastatic progression. Biol Direct. 2023 Aug 7;18(1):44. doi: 10.1186/s13062-023-00400-x. PMID: 37550720. (¥Co-First author)

3.Chu PY, Chou DA, Chen PM, Chiang EI. Translocation of Methionine Adenosyl Transferase MAT2A and Its Prognostic Relevance for Liver Hepatocellular Carcinoma. Int J Mol Sci. 2023 May 22;24(10):9103. doi: 10.3390/ijms24109103. PMID: 37240447.

4.Chen CC, Chu PY*, Lin HY*. Supervised Learning and Multi-Omics Integration Reveals Clinical Significance of Inner Membrane Mitochondrial Protein (IMMT) in Prognostic Prediction, Tumor Immune Microenvironment and Precision Medicine for Kidney Renal Clear Cell Carcinoma. Int J Mol Sci. 2023 May 15;24(10):8807. doi: 10.3390/ijms24108807. PMID: 37240154. (*Co-Corresponding author)

5.Lin HY, Wu HJ, Chu PY. Multi-omics and experimental analysis unveil theragnostic value and immunological roles of inner membrane mitochondrial protein (IMMT) in breast cancer. J Transl Med. 2023 Mar 10;21(1):189. doi: 10.1186/s12967-023-04035-4. PMID: 36899366.

6.Chen PM, Wong CN, Wong CN, Chu PY. Actin-like Protein 6A Expression Correlates with Cancer Stem Cell-like Features and Poor Prognosis in Ovarian Cancer. Int J Mol Sci. 2023 Jan 19;24(3):2016. doi: 10.3390/ijms24032016. PMID: 36768349.

7.Hsu HP¥, Chu PY¥, Chang TM¥, Huang KW, Hung WC, Jiang SS, Lin HY, Tsai HJ. Mitochondrial phosphoenolpyruvate carboxykinase promotes tumor growth in estrogen receptor-positive breast cancer via regulation of the mTOR pathway. Cancer Med. 2023 Jan;12(2):1588-1601. doi: 10.1002/cam4.4969. Epub 2022 Jun 27. PMID: 35757841. (¥Co-First author)

8.Chang TM, Chu PY¥, Lin HY, Huang KW, Hung WC, Shan YS, Chen LT, Tsai HJ. PTEN regulates invasiveness in pancreatic neuroendocrine tumors through DUSP19-mediated VEGFR3 dephosphorylation. J Biomed Sci. 2022 Nov 6;29(1):92. doi: 10.1186/s12929-022-00875-2. PMID: 36336681. (¥Co-First author)

9.Chen CC, Chu PY*, Lin HY*. Multi-Omics Analysis Reveals Clinical Value and Possible Mechanisms of ATAD1 Down-Regulation in Human Prostate Adenocarcinoma. Life (Basel). 2022 Oct 30;12(11):1742. doi: 10.3390/life12111742. PMID: 36362897. (*Co-Corresponding author)

10.Hu MH¥, Chu PY¥, Huang SM, Shih BS, Ko CL, Hu JJ, Chen WC. Injectability, Processability, Drug Loading, and Antibacterial Activity of Gentamicin-Impregnated Mesoporous Bioactive Glass Composite Calcium Phosphate Bone Cement In Vitro. Biomimetics (Basel). 2022 Aug 28;7(3):121. doi: 10.3390/biomimetics7030121. PMID: 36134925. (¥Co-First author)

11.Chu PY, Huang WC, Tung SL, Tsai CY, Chen CJ, Liu YC, Lee CW, Lin YH, Lin HY, Chen CY, Yeh CT, Lin KH, Chi HC. IFITM3 promotes malignant progression, cancer stemness and chemoresistance of gastric cancer by targeting MET/AKT/FOXO3/c-MYC axis. Cell Biosci. 2022 Aug 8;12(1):124. doi: 10.1186/s13578-022-00858-8. PMID: 35941699

12.Wu HJ, Chu PY. Current and Developing Liquid Biopsy Techniques for Breast Cancer. Cancers (Basel). 2022 Apr 19;14(9):2052. doi: 10.3390/cancers14092052. PMID: 35565189. Review

13.Chu PY, Tzeng YT, Tsui KH, Chu CY, Li CJ. Downregulation of ATP binding cassette subfamily a member 10 acts as a prognostic factor associated with immune infiltration in breast cancer. Aging (Albany NY). 2022 Mar 5;14(5):2252-2267. doi: 10.18632/aging.203933. Epub 2022 Mar 5. PMID: 35247251

14.Ko CJ, Gao SL, Lin TK, Chu PY*, Lin HY*. Ferroptosis as a Major Factor and Therapeutic Target for Neuroinflammation in Parkinson′s Disease. Biomedicines. 2021 Nov 12;9(11):1679. doi: 10.3390/biomedicines9111679. PMID: 34829907. Review. (*Co-Corresponding author)

15.Lin HY, Wu HJ, Chen SY, Hou MF, Lin CS, Chu PY. Epigenetic therapy combination of UNC0638 and CI-994 suppresses breast cancer via epigenetic remodeling of BIRC5 and GADD45A. Biomed Pharmacother. 2021 Nov 16;145:112431. doi: 10.1016/j.biopha.2021.112431.

16.Chu PY, Chan SH. Cure the Incurable? Recent Breakthroughs in Immune Checkpoint Blockade for Hepatocellular Carcinoma. Cancers (Basel). 2021 Oct 22;13(21):5295. doi: 10.3390/cancers13215295. PMID: 34771459. Review.

17.Huang WC, Chi HC, Tung SL, Chen PM, Shih YC, Huang YC, Chu PY. Identification of the Novel Tumor Suppressor Role of FOCAD/miR-491-5p to Inhibit Cancer Stemness, Drug Resistance and Metastasis via Regulating RABIF/MMP Signaling in Triple Negative Breast Cancer. Cells. 2021 Sep 24;10(10):2524. doi: 10.3390/cells10102524. PMID: 34685504

18.Chu PY, Tzeng YT, Chiu YH, Lin HY, Kuo CH, Hou MF, Li CJ. Multi-Omics Reveals the Immunological Role and Prognostic Potential of Mitochondrial Ubiquitin Ligase MARCH5 in Human Breast Cancer. Biomedicines. 2021 Sep 26;9(10):1329. doi: 10.3390/biomedicines9101329. PMID: 34680446

19.Lin HY, Ho HW, Chang YH, Wei CJ, Chu PY. The Evolving Role of Ferroptosis in Breast Cancer: Translational Implications Present and Future. Cancers (Basel). 2021 Sep 12;13(18):4576. doi: 10.3390/cancers13184576. PMID: 34572802. Review.

20.Wu HJ, Chu PY. Epigenetic Regulation of Breast Cancer Stem Cells Contributing to Carcinogenesis and Therapeutic Implications. Int J Mol Sci. 2021 Jul 29;22(15):8113. doi: 10.3390/ijms22158113. PMID: 34360879. Review.

21.Yang YL, Tsai MC, Chang YH, Wang CC, Chu PY*, Lin HY*, Huang YH*. MIR29A Impedes Metastatic Behaviors in Hepatocellular Carcinoma via Targeting LOX, LOXL2, and VEGFA. Int J Mol Sci. 2021 Jun 1;22(11):6001. doi: 10.3390/ijms22116001. PMID: 34206143. (*Co-Corresponding author)

22.Li CJ, Tzeng YT, Chiu YH, Lin HY, Hou MF, Chu PY*. Pathogenesis and Potential Therapeutic Targets for Triple-Negative Breast Cancer. Cancers (Basel). 2021 Jun 14;13(12):2978. doi: 10.3390/cancers13122978. PMID: 34198652. Review.

23.Huang YH¥, Chu PY¥, Chen JL, Huang CT, Huang CC, Tsai YF, Wang YL, Lien PJ, Tseng LM, Liu CY. Expression pattern and prognostic impact of glycoprotein non-metastatic B (GPNMB) in triple-negative breast cancer. Sci Rep. 2021 Jun 9;11(1):12171. doi: 10.1038/s41598-021-91588-3. PMID: 34108545. (¥Co-First author)

24.Chu PY, Wu HJ, Wang SM, Chen PM, Tang FY, Chiang EI. MAT2A Localization and Its Independently Prognostic Relevance in Breast Cancer Patients. Int J Mol Sci. 2021 May 20;22(10):5382. doi: 10.3390/ijms22105382. PMID: 34065390.

25.Lin HY, Chu PY*. Advances in Understanding Mitochondrial MicroRNAs (mitomiRs) on the Pathogenesis of Triple-Negative Breast Cancer (TNBC). Oxid Med Cell Longev. 2021 Mar 22;2021:5517777. doi: 10.1155/2021/5517777. eCollection 2021. PMID: 33824695. Review.

26.Yang YL, Chang YH, Li CJ, Huang YH, Tsai MC, Chu PY*, Lin HY*. New Insights the Role of miR-29a in Hepatocellular Carcinoma: Implications in Mechanisms and Theragnostics. J Pers Med. 2021 Mar 18;11(3):219. doi: 10.3390/jpm11030219. PMID: 33803804. Review.

27.Wu HJ, Chu PY*. Recent Discoveries of Macromolecule- and Cell-Based Biomarkers and Therapeutic Implications in Breast Cancer. Int J Mol Sci. 2021 Jan 10;22(2):636. doi: 10.3390/ijms22020636.PMID: 33435254. Review.

28.Li CJ, Lin LT, Hou MF, Chu PY*. PD‑L1/PD‑1 blockade in breast cancer: The immunotherapy era. Oncol Rep. 2021 Jan;45(1):5-12. doi: 10.3892/or.2020.7831. Epub 2020 Nov 3. PMID: 33416128. Review.

29.Lin HY, Li CJ, Yang YL, Huang YH, Hsiau YT, Chu PY*. Roles of Lysyl Oxidase Family Members in the Tumor Microenvironment and Progression of Liver Cancer. Int J Mol Sci. 2020 Dec 21;21(24):9751. doi: 10.3390/ijms21249751. PMID: 33371259

30.Li CJ, Lin HY, Ko CJ, Lai JC, Chu PY*. A Novel Biomarker Driving Poor-Prognosis Liver Cancer: Overexpression of the Mitochondrial Calcium Gatekeepers. Biomedicines. 2020 Oct 24;8(11):451. doi: 10.3390/biomedicines8110451. PMID: 33114428

31.Chu PY¥, Wang SM¥, Chen PM¥, Tang FY, Chiang EI. Expression of MTDH and IL-10 Is an Independent Predictor of Worse Prognosis in ER-Negative or PR-Negative Breast Cancer Patients. J Clin Med. 2020 Sep 29;9(10):3153. doi: 10.3390/jcm9103153. PMID: 33003428 (¥Co-First author)

32.Chu PY¥, Tung SL¥, Tsai KW¥, Shen FP, Chan SH. Identification of the Novel Oncogenic Role of SAAL1 and Its Therapeutic Potential in Hepatocellular Carcinoma. Cancers (Basel). 2020 Jul 8;12(7):E1843. doi: 10.3390/cancers12071843. PMID: 32650537 (¥Co-First author)

33.Wang SM, Chen PM, Sung YW, Huang WC, Huang HS, Chu PY*. Effect of COL4A1 Expression on the Survival of Neoadjuvant Chemotherapy Breast Cancer Patients. J Oncol. 2020 May 14;2020:5209695. doi: 10.1155/2020/5209695. eCollection 2020. PMID: 32565804

34.Chang JS¥, Kuo SH¥, Chu PY¥, Shan YS, Tsai CR, Tsai HJ, Chen LT (2019, Oct). The Epidemiology of Gastric Cancers in the Era of Helicobacter pylori Eradication: A Nationwide Cancer Registry-Based Study in Taiwan. Cancer Epidemiol Biomarkers Prev, 28(10):1694-1703. (¥Co-First author)

35.Li CJ¥, Chu PY¥, Yiang GT, Wu MY. The Molecular Mechanism of Epithelial-Mesenchymal Transition for Breast Carcinogenesis. Biomolecules. 2019 Sep 11;9(9). pii: E476. doi: 10.3390/biom9090476. Review. (¥Co-First author)

36.Wu HJ, Chu PY*. Role of Cancer Stem Cells in Cholangiocarcinoma and Therapeutic Implications. Int J Mol Sci. 2019 Aug 25;20(17). pii: E4154. doi: 10.3390/ijms20174154. Review. PMID: 31450710. (*Corresponding author)

37.Tsui KH, Wu MY, Lin LT, Wen ZH, Li YH, Chu PY*, Li CJ*. Disruption of mitochondrial homeostasis with artemisinin unravels anti-angiogenesis effects via auto-paracrine mechanisms. Theranostics 2019 Sep 17; 9(22):6631-6645. doi:10.7150/thno.33353. (*Co-Corresponding author)

38.Chu PY, Hou MF, Lai JC, Chen LF, Lin CS. Cell Reprogramming in Tumorigenesis and Its Therapeutic Implications for Breast Cancer. Int J Mol Sci. 2019 Apr 12;20(8). pii: E1827. doi: 10.3390/ijms20081827. Review. PMID: 31013830.