就業狀態

Employment
【2004-10~NOW】National Chung Hsing University:Taichung, Taiwan, TW
【2012-02~2013-01】University of Texas Southwestern Medical Center:Dallas, TX, US

教育與認證

Education and qualifications
【1995-09~2000-06】National Yang-Ming University:Taipei, Taiwan, TW

成果

Works
【2021-06 Biomolecules】RET Regulates Human Medullary Thyroid Cancer Cell Proliferation through CDK5 and STAT3 Activation
【2021-02 Biomedicines】Bacterial Genotoxin-Coated Nanoparticles for Radiotherapy Sensitization in Prostate Cancer
【2021-02 Chemosphere】Regulation of extracellular and intracellular prolactin on cell proliferation and survival rate through GHR/JAK2/STAT3 pathway in NSCLC
【2021-01 Integrative cancer therapies】Inhibitory Effects of Digoxin and Digitoxin on Cell Growth in Human Ovarian Cancer Cell Line SKOV-3.
【2020-11 Molecular imaging and biology】The Roles of ZnT1 and ZnT4 in Glucose-Stimulated Zinc Secretion in Prostate Epithelial Cells.
【2020-04 Cell Death & Disease】RAGE acts as an oncogenic role and promotes the metastasis of human lung cancer
【2020- International Journal of Medical Sciences】Aqueous Ocimum gratissimum extract induces cell apoptosis in human hepatocellular carcinoma cells
【2019-07 Clinical Cancer Research】Downregulation of Human DAB2IP Gene Expression in Renal Cell Carcinoma Results in Resistance to Ionizing Radiation
【2019-06 Cell Death & Disease】The roles and mechanism of IFIT5 in bladder cancer epithelial–mesenchymal transition and progression
【2019-03 Toxins】Arecoline Promotes Migration of A549 Lung Cancer Cells through Activating the EGFR/Src/FAK Pathway
【2019- International Journal of Molecular Sciences】Future aspects of CDK5 in prostate cancer: From pathogenesis to therapeutic implications
【2019- Cancer Research】IFNG-induced IFIT5 promotes epithelial-to-mesenchymal transition in prostate cancer via miRNA processing
【2019- Chinese Journal of Physiology】Mechanistic insight of cyclin-dependent kinase 5 in modulating lung cancer growth
【2019- Cell Death and Disease】The paracrine induction of prostate cancer progression by caveolin-1
【2018-12 Cancers】Antrocin Sensitizes Prostate Cancer Cells to Radiotherapy through Inhibiting PI3K/AKT and MAPK Signaling Pathways
【2018- 調適醫學】The Inhibitory Effect of Roscovitine on Prostate Cancer Cell Proliferation and Androgen Receptor Phosphorylation
【2017-05 Oncotarget】The network of DAB2IP-miR-138 in regulating drug resistance of renal cell carcinoma associated with stem-like phenotypes
【2017- Frontiers in Cellular and Infection Microbiology】Cytolethal Distending Toxin Enhances Radiosensitivity in Prostate Cancer Cells by Regulating Autophagy
【2017- Cancer Letters】Induction of neuroendocrine differentiation in castration resistant prostate cancer cells by adipocyte differentiation-related protein (ADRP) delivered by exosomes
【2017- Adaptation Biology and Medicine: Volume 8】Resveratrol inhibits the growth of prostate cancer cells through decreasing androgen receptor phosphorylation and protein stability
【2017- PLoS ONE】Sensitization of radioresistant prostate cancer cells by resveratrol isolated from arachis hypogaea stems
【2016- Current Genetics】A new rapid and efficient with dominant ion developed to inactivate and conditionally express genes in Candida albicans
【2016- Cancer Research】Cdk5 directly targets nuclear p21CIP1 and promotes cancer cell growth
【2016- 調適醫學】Involvement of Cholecystokinin (CCK) Receptor in the Adaptation of Gastric Emptying Induced by Adrenocorticotropin (ACTH) in Male Rats
【2016- 調適醫學】Involvement of Cholecystokinin (CCK) Receptor in the Regulation of Dexamethasone on Gastric Emptying in Male Rats
【2016- BMC Complementary and native Medicine】Kinsenoside inhibits the inflammatory mediator release in a type-II collagen induced arthritis mouse model by regulating the T cells responses
【2016- Frontiers in Cellular and Infection Microbiology】Molecular mechanisms and potential clinical applications of Campylobacter jejuni cytolethal distending toxin
【2016- Oncotarget】MZF-1/Elk-1 interaction domain as therapeutic target for protein kinase Cα-based triple-negative breast cancer cells
【2016- International Journal of Molecular Sciences】N-glycosylation of human R-spondin 1 is required for efficient secretion and stability but not for its heparin binding ability
【2016- Molecular Medicine Reports】Protein kinase C α is involved in the regulation of AXL receptor tyrosine kinase expression in triple-negative breast cancer cells
【2016- Chinese Journal of Physiology】Suppression of breast cancer cell growth by her2-reduced AR serine 81 phosphorylation
【2016- Oncotarget】Targeting XBP1-mediated β-catenin expression associated with bladder cancer with newly synthetic Oridonin analogues
【2015- PLoS ONE】Correction: MZF-1/Elk-1 complex binds to protein kinase Cα promoter and is involved in hepatocellular carcinoma
【2015- BioMedicine (Netherlands)】Impact of cholesterol on disease progression
【2015- PLoS ONE】MZF-1/Elk-1 complex binds to protein kinase Cα promoter and is involved in hepatocellular carcinoma
【2014- Cellular Physiology and Biochemistry】All-trans retinoic acid induces DU145 cell cycle arrest through Cdk5 activation
【2014- Neurobiology of Aging】Antineuroinflammatory effects of lycopene via activation of adenosine monophosphate-activated protein kinase-α1/heme oxygenase-1 pathways
【2014- 調適醫學】Involvement of the Target Proteins in the Investigation to Prognostic Model for Breast Cancer
【2014- BioMedicine (Netherlands)】Retinoic acid and cancer treatment
【2014- PLoS ONE】Susceptibility of Human Embryonic Stem Cell-Derived Neural Cells to Japanese Encephalitis Virus Infection
【2013- American Journal of Physiology - Endocrinology and Metabolism】Cyclin-dependent kinase 5 modulates STAT3 and androgen receptor activation through phosphorylation of ser727 on STAT3 in prostate cancer cells
【2013- Evidence-Based Complementary and native Medicine】Emodin and Aloe-Emodin Suppress Breast Cancer Cell Proliferation through ERαInhibition
【2013- International Journal of Radiation Biology】Inhibitory effects of Rhenium-188-labeled Herceptin on prostate cancer cell growth: A possible radioimmunotherapy to prostate carcinoma
【2013- Osteoporosis International】Kinsenoside prevents ovariectomy-induced bone loss and suppresses osteoclastogenesis by regulating classical NF-κB pathways
【2013- The FASEB Journal】Lycopene Inhibits Cyclooxygenase-2 And Inflammatory Mediator Expression In Microglia
【2013- Surgical Science】Spontaneous Rupture of the Bladder after a Seizure: A Pitfall of Diagnosis
【2012- PLoS ONE】5-fluorouracil induced intestinal mucositis via nuclear factor-κB activation by transcriptomic analysis and in vivo bioluminescence imaging
【2012- PLoS ONE】Desipramine Protects Neuronal Cell Death and Induces Heme Oxygenase-1 Expression in Mes23.5 Dopaminergic Neurons
【2012- Evidence-based Complementary and native Medicine】Erratum: Study of the anti-proliferative activity of 5-substituted 4,7-dimethoxy-l,3-benzodioxole derivatives of SY-1 from antrodia camphorata on human COLO 205 colon cancer cells (Evidence-based Complementary and native Medicine)
【2012- 調適醫學】Inhibitory Effects of Digoxin on Testosterone Production in Rat Leydig Cells